The beaches north and south of Mandurah are renowned for producing mulloway and tailor, along with herring. Inside the estuary, there is excellent fishing around the Dawesville Cut for tailor, herring, skippy and juvenile salmon, as well as king george and yellowfin whiting.

Crabbing is a hugely popular pastime in the estuary, and herring and yellowfin whiting fishing can be very good in the shallows. The Serpentine and Murray rivers are excellent black bream fisheries.